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Chronic Respiratory Failure

What is Chronic Respiratory Failure?

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Chronic respiratory failure occurs when the lungs can no longer efficiently exchange gases, resulting in low oxygen levels (hypoxemia) and/or high carbon dioxide levels (hypercapnia) in the blood over an extended period. It is often caused by underlying lung or neuromuscular diseases.

Causes of Chronic Respiratory Failure:

  • Chronic obstructive pulmonary disease (COPD)
  • Interstitial lung disease (ILD)
  • Neuromuscular disorders (e.g., muscular dystrophy, ALS)
  • Obesity hypoventilation syndrome
  • Severe asthma
  • Chest wall deformities (e.g., scoliosis)
  • Sleep apnea (long-term untreated cases)

Common Signs and Symptoms:

  • Shortness of breath, especially with exertion
  • Fatigue and weakness
  • Confusion or difficulty concentrating (due to high CO2 levels)
  • Morning headaches (due to CO2 buildup)
  • Cyanosis (bluish tint to lips or skin from low oxygen)
  • Reduced exercise tolerance

Popular Treatment Methods:

  • Oxygen therapy: To increase blood oxygen levels
  • Non-invasive ventilation: CPAP or BiPAP to assist breathing
  • Medications: Bronchodilators or corticosteroids (for underlying conditions like COPD or asthma)
  • Pulmonary rehabilitation: Exercise and education to improve lung function
  • Lung transplant: In severe, advanced cases
  • Lifestyle changes: Smoking cessation, weight management, or avoiding triggers

Chronic respiratory failure is a serious condition, but with proper treatment, symptoms can be managed, and quality of life can be improved.

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